A dental partner in your patients’ systemic health.
BU Dental is an oral-systemic practice in Pleasant Hill. We identify and treat active oral infection and inflammation — one of the few modifiable inflammatory burdens your patients carry — and, with their consent, we report what we find back to you.
Why a dentist belongs on the care team
Chronic periodontal disease is a treatable bacterial infection, and the research literature consistently associates it with the conditions you manage: cardiovascular disease, glycaemic control in diabetes, adverse pregnancy outcomes, and sleep-disordered breathing. We are deliberate about the language — these are documented associations, with interventional evidence still maturing — and we link the primary sources below rather than overstating them. What is not in dispute: active oral infection adds to a patient’s total inflammatory load, and it responds to treatment.
If you practice functional, integrative, or lifestyle medicine, this is likely the piece of the inflammation picture you cannot examine yourself. We can.
Patients we can help you with
- Patients managing type 2 diabetes or prediabetes, where gum inflammation and glycaemic control interact in both directions
- Patients with cardiovascular risk factors and untreated or unexamined periodontal disease
- Pregnant patients — preventive dental care during pregnancy is safe and recommended, and hormonal changes make gum tissue more reactive
- Patients with suspected sleep-disordered breathing, bruxism, or airway concerns, including candidates for oral appliance therapy
- Patients with persistent systemic inflammation where an active oral source has not been ruled out
What your patient’s evaluation includes
- Comprehensive periodontal examination
- Full charting and an in-depth clinical exam of gum health and active dental conditions.
- Live phase contrast microscopy
- We sample plaque and examine it under the microscope at the visit itself — the patient sees their own slide — to profile periodontal and systemic disease risk.
- Comprehensive pathogen report
- When in-office findings show moderate or high risk, we add a Fida Labs comprehensive periodontal pathogen report, so treatment is guided by the patient’s actual flora rather than a default protocol.
- Radiographs & iTero digital scan
- Bone, roots, and teeth; bite, alignment, and occlusion.
- Airway & bruxism assessment
- Airway look, bite, and signs of grinding — the dental findings that travel with sleep-disordered breathing. Diagnosis remains medical; our role is to notice, evaluate, and refer back.
- Oral cancer screening & full health history
- Including medical history, medications, diet, and home care — the first visit runs about 90 minutes.
About the pathogen panel
The comprehensive oral pathogen panel we use (Fida Labs) is a saliva-based assay reporting two sets of organisms: periodontal pathogens — including P. gingivalis, T. forsythia, T. denticola, A. actinomycetemcomitans, and the F. nucleatum subspecies — and the cariogenic species behind decay, chiefly S. mutans (including the collagen-binding cnm+ strain) and S. sobrinus. Candida and herpesviruses are reported when detected.
Results come back as risk-stratified composite scores for each panel, plus the individual species that exceed their reporting thresholds. That stratification drives recall interval, whether targeted rather than conventional therapy is indicated, and what we retest after treatment — which is the part most relevant to you, since it turns "we treated the gums" into a measured before-and-after.
If a specific patient's report would be useful to you, we're glad to walk through it. The patient-facing explanation is here.
What you receive back
- A findings summary after the comprehensive evaluation: periodontal status, microscopy findings, and the pathogen report when one was indicated
- The treatment plan and its rationale
- Status updates at re-evaluation, so you can see whether the oral inflammatory burden is actually coming down
Communication goes through the channel you prefer. We do not collect patient information through this website — records move directly between our offices.
How to refer
- Have your patient call us at (925) 687-0343 and mention your name or practice — no forms, no portal.
- Or call us first. If you’d like to discuss whether a patient is a good fit, Dr. Uddaraju is happy to talk it through before anyone is scheduled.
- Send records your way. Use whatever secure channel your practice already trusts; our front office will coordinate.
Print the one-page referral sheet → — a summary of all of this for your exam rooms or front desk.
The evidence we practice from
The same peer-reviewed sources we cite to patients on the mouth–body connection pages — linked so you can weigh the primary literature yourself.
Brain
- Dominy, S. S., et al. (2019). Porphyromonas gingivalis in Alzheimer’s disease brains: Evidence for disease causation and treatment with small-molecule inhibitors. Science Advances, 5(1), eaau3333.
- Kanagasingam, S., Chukkapalli, S. S., Welbury, R., & Singhrao, S. K. (2020). Porphyromonas gingivalis is a Strong Risk Factor for Alzheimer’s Disease. Journal of Alzheimer’s Disease Reports, 4(1), 501–511.
Sleep & airway
- Li, D., Kuang, B., Lobbezoo, F., de Vries, N., Hilgevoord, A., & Aarab, G. (2023). Sleep bruxism is highly prevalent in adults with obstructive sleep apnea: a large-scale polysomnographic study. Journal of Clinical Sleep Medicine, 19(3), 443–451.
- Molina, A., Huck, O., Herrera, D., & Montero, E. (2023). The association between respiratory diseases and periodontitis: A systematic review and meta-analysis. Journal of Clinical Periodontology, 50(6), 842–887.
Cardiovascular
- Lockhart, P. B., et al. (2012). Periodontal disease and atherosclerotic vascular disease: a scientific statement from the American Heart Association. Circulation, 125(20), 2520–2544.
- Arbildo-Vega, H. I., et al. (2024). Periodontal disease and cardiovascular disease: umbrella review. BMC Oral Health, 24(1), 1308.
- Tran, A. H., et al. (2026). Periodontal Disease and Atherosclerotic Cardiovascular Disease: A Scientific Statement From the American Heart Association. Circulation, 153(6), e73–e88. (Published online December 16, 2025.)
Metabolic
- Sanz, M., et al. (2018). Scientific evidence on the links between periodontal diseases and diabetes: consensus report of the joint IDF/EFP workshop. Journal of Clinical Periodontology, 45(2), 138–149.
- Simpson, T. C., et al. (2022). Treatment of periodontitis for glycaemic control in people with diabetes mellitus. Cochrane Database of Systematic Reviews, (4), CD004714.
Respiratory
- Molina, A., Huck, O., Herrera, D., & Montero, E. (2023). The association between respiratory diseases and periodontitis: A systematic review and meta-analysis. Journal of Clinical Periodontology, 50(6), 842–887.
- Gomes-Filho, I. S., et al. (2020). Periodontitis and respiratory diseases: A systematic review with meta-analysis. Oral Diseases, 26(2), 439–446.
- Sjögren, P., Nilsson, E., Forsell, M., Johansson, O., & Hoogstraate, J. (2008). A systematic review of the preventive effect of oral hygiene on pneumonia and respiratory tract infection in elderly people in hospitals and nursing homes. Journal of the American Geriatrics Society, 56(11), 2124–2130.
- Apessos, I., Voulgaris, A., Agrafiotis, M., Andreadis, D., & Steiropoulos, P. (2021). Effect of periodontal therapy on COPD outcomes: a systematic review. BMC Pulmonary Medicine, 21(1), 92.
Bone & joints
- Ruggiero, S. L., Dodson, T. B., Aghaloo, T., Carlson, E. R., Ward, B. B., & Kademani, D. (2022). American Association of Oral and Maxillofacial Surgeons’ Position Paper on Medication-Related Osteonecrosis of the Jaws — 2022 Update. Journal of Oral and Maxillofacial Surgery, 80(5), 920–943.
- Sollecito, T. P., et al. (2015). The use of prophylactic antibiotics prior to dental procedures in patients with prosthetic joints: Evidence-based clinical practice guideline for dental practitioners — a report of the American Dental Association Council on Scientific Affairs. Journal of the American Dental Association, 146(1), 11–16.e8.
- American Academy of Orthopaedic Surgeons (2025). AAOS Clinical Practice Guideline Summary: Prevention of Total Hip and Knee Arthroplasty Periprosthetic Joint Infection in Patients Undergoing Dental Procedures. Journal of the American Academy of Orthopaedic Surgeons, 33(21), e1260–e1267.
- Penoni, D. C., Fidalgo, T. K. S., Torres, S. R., Varela, V. M., Masterson, D., Leão, A. T. T., & Maia, L. C. (2017). Bone Density and Clinical Periodontal Attachment in Postmenopausal Women: A Systematic Review and Meta-Analysis. Journal of Dental Research, 96(3), 261–269.
- Chaves, J. D. P., Figueredo, T. F. M., Warnavin, S. V. S. C., Pannuti, C. M., & Steffens, J. P. (2020). Sex hormone replacement therapy in periodontology — A systematic review. Oral Diseases, 26(2), 270–284.
Autoimmune
- Dolcezza, S., Flores-Fraile, J., Lobo-Galindo, A. B., Montiel-Company, J. M., & Zubizarreta-Macho, Á. (2025). Relationship Between Rheumatoid Arthritis and Periodontal Disease — Systematic Review and Meta-Analysis. Journal of Clinical Medicine, 14(1), 10.
- Fuggle, N. R., Smith, T. O., Kaul, A., & Sofat, N. (2016). Hand to Mouth: A Systematic Review and Meta-Analysis of the Association between Rheumatoid Arthritis and Periodontitis. Frontiers in Immunology, 7, 80.
Digestive tract
- She, Y.-Y., Kong, X.-B., Ge, Y.-P., Liu, Z.-Y., Chen, J.-Y., Jiang, J.-W., Jiang, H.-B., & Fang, S.-L. (2020). Periodontitis and inflammatory bowel disease: a meta-analysis. BMC Oral Health, 20(1), 67.
- Wang, Q., Gu, W.-J., Ning, F.-L., Sun, M., Zhao, Z.-M. G., Abe, M. U., Li, Z.-N., & Zhang, C.-D. (2024). Association between Periodontal Diseases and the Risk of Site-Specific Gastrointestinal Cancers: A Systematic Review and Meta-Analysis. Journal of Dental Research, 103(10), 962–972.
Cancer
- Zeng, X.-T., Deng, A.-P., Li, C., Xia, L.-Y., Niu, Y.-M., & Leng, W.-D. (2013). Periodontal disease and risk of head and neck cancer: a meta-analysis of observational studies. PLoS ONE, 8(10), e79017.
- Wang, Q., Gu, W.-J., Ning, F.-L., Sun, M., Zhao, Z.-M. G., Abe, M. U., Li, Z.-N., & Zhang, C.-D. (2024). Association between Periodontal Diseases and the Risk of Site-Specific Gastrointestinal Cancers: A Systematic Review and Meta-Analysis. Journal of Dental Research, 103(10), 962–972.
- Michaud, D. S., Izard, J., Wilhelm-Benartzi, C. S., et al. (2013). Plasma antibodies to oral bacteria and risk of pancreatic cancer in a large European prospective cohort study. Gut, 62(12), 1764–1770.
Let’s talk about a patient — or a partnership.
Coffee, a lunch-and-learn for your team, or a fifteen-minute call: whatever is easiest. We’re at 401 Gregory Lane, Suite 218, Pleasant Hill — a short drive from Walnut Creek, Concord, Martinez, and Lafayette.
This page describes associations reported in peer-reviewed research and the services of a dental practice. It is not medical advice. Content pending clinical review by Dr. Uddaraju and Dr. Bautista.